“the obesity code fasting +solutions to help childhood obesity”

Jump up ^ Berrington de Gonzalez A, Hartge P, Cerhan JR, Flint AJ, Hannan L, MacInnis RJ, Moore SC, Tobias GS, Anton-Culver H, Freeman LB, Beeson WL, Clipp SL, English DR, Folsom AR, Freedman DM, Giles G, Hakansson N, Henderson KD, Hoffman-Bolton J, Hoppin JA, Koenig KL, Lee IM, Linet MS, Park Y, Pocobelli G, Schatzkin A, Sesso HD, Weiderpass E, Willcox BJ, Wolk A, Zeleniuch-Jacquotte A, Willett WC, Thun MJ (2010). “Body-mass index and mortality among 1.46 million white adults”. The New England Journal of Medicine. 363 (23): 2211–19. doi:10.1056/NEJMoa1000367. PMC 3066051 . PMID 21121834.
Lambert et al. (2008) recruited 16 obese frail, older men and women, and also used a similar inclusion criteria and interventions to Villareal (2006a), although the intervention was only three months. A vastus lateralis biopsy was used to quantify mRNA expression of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α), Toll-like receptor 4 (TLR-4) and mechano growth factor (MGF). Serum IL-6 and TNF-α also obtained. Body weight and FFM significantly decreased in the weight loss group, while FFM increased in the exercise group. Toll-like receptor 4 mRNA significantly decreased in the exercise group, but did not change in the weight loss group. IL-6 and TNF-α mRNA decreased and MGF mRNA increased in the exercise group, but not in the weight loss group. It was concluded that cytokine gene expression appeared to be derived from muscle, as serum concentrations of TNF-α and IL-6 did not change with exercise. The investigators proposed that exercising muscle contraction decreased muscle inflammatory cytokine expression, whereas weight loss had no effect. The proposed mechanism was down regulation of TLR-4 mRNA (Flynn 2006). The study investigators also suggested that the lack of a significant effect of weight loss on TNFα-mRNA may indicate that a threshold of weight loss is needed. They concluded that exercise, but not weight loss, down regulates mRNA expression of TLR-4, TNF-α and IL-6, which is related to increased muscle catabolism, while up-regulating mRNA expression of MGF in skeletal muscle.
“This is a social issue,” former president Bill Clinton told the audience at a recent summit on obesity, as he accepted an award for the work of his group, the Alliance for a Healthier Generation. “We are trying to turn the Titanic around before it hits the iceberg.”
Psychosocial effects – In a culture where often the ideal of physical attractiveness is to be overly thin, people who are overweight or obese frequently suffer disadvantages. Overweight and obese persons are often blamed for their condition and may be considered to be lazy or weak-willed. It is not uncommon for overweight or obese conditions to result in persons having lower incomes or having fewer or no romantic relationships. Disapproval of overweight persons expressed by some individuals may progress to bias, discrimination, and even torment.
Meyerhardt JA, Tepper JE, Niedzwiecki D, et al. Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114. Journal of Clinical Oncology 2004; 22(4):648-657.
Jump up ^ Rosén T, Bosaeus I, Tölli J, Lindstedt G, Bengtsson BA (1993). “Increased body fat mass and decreased extracellular fluid volume in adults with growth hormone deficiency”. Clin. Endocrinol. 38 (1): 63–71. doi:10.1111/j.1365-2265.1993.tb00974.x. PMID 8435887.
Moyer VA; U.S. Preventive Services Task Force. Screening for and management of obesity in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2012;157(5):373-378. PMID: 22733087 www.ncbi.nlm.nih.gov/pubmed/22733087.
One of the two major types of diabetes, the type in which the beta cells of the pancreas produce insulin but the body is unable to use it effectively because the cells of the body are resistant to the action of insulin. Although this type of diabetes may not carry the same risk of death from ketoacidosis, it otherwise involves many of the same risks of complications as does type 1 diabetes (in which there is a lack of insulin).
Treatment for overweight and obesity depends on the cause and severity of your condition. Possible treatments include healthy lifestyle changes, behavioral weight-loss treatment programs, medicines, and possibly surgery. You may need treatments for any complications that you have.
Jump up ^ Nestle, Marion (12 September 2016). “Invited Commentary: Food Industry Funding of Nutrition Research: The Relevance of History for Current Debates”. JAMA Internal Medicine. 176 (11): 1685–86. doi:10.1001/jamainternmed.2016.5400. PMID 27618496.
“Phen-fen” and Redux: These prescription drugs have been removed from the market in the United States and many other countries. They are linked to heart-valve problems and pulmonary hypertension. Pulmonary hypertension affects the blood vessels in the lungs and is often fatal.
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Jump up ^ Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW (October 1999). “Body-mass index and mortality in a prospective cohort of U.S. adults”. N. Engl. J. Med. 341 (15): 1097–105. doi:10.1056/NEJM199910073411501. PMID 10511607.
“Obese patients are nearly 12 times more likely to suffer a complication following elective plastic surgery than their normal-weight counterparts” according to hopkinsmedicine.org (Ref. http://bit.ly/za1Vmh).
Medication treatment of obesity should be used only in patients who have health risks related to obesity. Medications should be used in patients with a BMI greater than 30 or in those with a BMI of greater than 27 who have other medical conditions (such as high blood pressure, diabetes, high blood cholesterol) that put them at risk for developing heart disease. Medications should not be used for cosmetic reasons.
Gastric bypass surgery—helps you lose weight by changing how your stomach and small intestine handle the food you eat. After the surgery, you will not be able to eat as much as before, and your body will not absorb all the calories and other nutrients from the food you eat.
For those who are overweight or obese, losing weight may help reduce the risk of developing osteoarthritis. Weight loss of at least 5 percent of your body weight may decrease stress on your knees, hips, and lower back and lessen inflammation in your body.
Sense of thirst can decline with age, so drinking enough water is important for preventing dehydration. Fluids such as soda or fruit juice add a lot of calories, Campbell notes, and it’s not good for people with diabetes to drink juice all day. Instead, she suggests flavored water or water with a slice of lemon. She has good news for coffee and tea lovers: Caffeine is not as dehydrating as once thought.

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