Allopurinol, angiotensin-converting enzyme inhibitors, antibiotics, anticholinergics, antihistamines, calcium channel blockers, levodopa, propranolol, selegiline (Eldypryl), spironolactone (Aldactone)
Kelly et al. (2011) recruited 28 sedentary, obese adults who were weight stable for the previous six months. The group was randomly allocated to exercise plus either a low-glycemic index (LGI) or high-glycemic index (HGI) diet. Participants engaged in five exercise sessions per week for 60 minutes at 85% maximum heart rate. All food was provided and balanced for macronutrients and both groups lost similar amounts of weight over the six month intervention. Weight, FM, FFM, truncal fat, fasting plasma glucose and insulin decreased in both groups, but did not differ between groups. Glycemic response reduced only in the LGI group. Plasma and mononuclear cells (MNC)-derived TNFα reduced in the LGI group, but increased in the HGI group. Secretion of IL-6 from MNC and plasma IL-6 and monocyte chemotactic protein-1 (MCP-1) was reduced in the LGI group. Change in MNC-derived TNFα and plasma MCP-1 correlated with decreased glycemic response. It was concluded that a LGI diet plus exercise decreased inflammatory markers, whereas a HGI diet attenuated improvements in glycemia and inflammation that usually occur with exercise. One proposed mechanism was the production of nicotinamide adenine dinucleotide phosphate (NADPH), which results in reactive oxygen species that activates the NFkB pathway, and increases TNF-α (Mohanty 2000; Evans 2002; Ghanim 2004). Hypertrophied adipocytes in obesity are partially responsible for the secretion of IL-6, and are thus regulated by not only weight loss, but also hyperglycemia and physical activity. The decrease of MCP-1 in the LGI group associated with changes in plasma glucose was attributed to reduced stimulus to recruit MNC into adipose tissue, seen as improved glucose tolerance. This implies an improvement in adipose tissue function, and the investigators concluded that eating a LGI diet in combination with aerobic exercise can reverse the effects of obesity on proinflammatory cytokines, which appears independent of weight loss.
Given that many older adults suffer from obesity, you will likely have some of these clients coming to you for help in losing fat and increasing muscle mass and strength. Of course, strength training along with sensible eating can be instrumental in bringing about desired changes in overall body composition. Using the workouts in chapter 4, you can easily adjust training loads or resistances to match current strength levels while selecting exercises that can be performed safely on sturdy and properly sized machine and free-weight equipment.
Jump up ^ Mead, Emma; Brown, Tamara; Rees, Karen; Azevedo, Liane B.; Whittaker, Victoria; Jones, Dan; Olajide, Joan; Mainardi, Giulia M.; Corpeleijn, Eva (2017). “Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years”. The Cochrane Database of Systematic Reviews. 6: CD012651. doi:10.1002/14651858.CD012651. ISSN 1469-493X. PMID 28639319.
Erica Sanderson is a former content producer and editor for HealthCentral. Living with a chronic disorder that affects the lungs and instestine, Erica focused on covering digestive health and respiratory health. Topics included COPD, asthma, acid reflux, managing symptoms and medication.
Strokes: Being overweight or obese can lead to a buildup of plaque in your arteries. This causes blood clots to form, which can eventually reach the blood stream and then vital such as the brain or the heart, blocking blood flow and producing a stroke.
The next class (category) of drugs changes the metabolism of fat. Orlistat (Xenical, alli) is the only drug of this category that is U.S. FDA approved. This is a class of anti-obesity drugs called lipase inhibitors, or fat blockers. Fat from food can only be absorbed into the body after being broken up (a process called digestion) by digestive enzymes called lipases in the intestines. By inhibiting the action of lipase enzymes, orlistat prevents the intestinal absorption of fat by 30%. Drugs in this class do not affect brain chemistry. Theoretically, orlistat also should have minimal or no systemic side effects (side effects in other parts of the body) because the major locale of action is inside the gut lumen and very little of the drug is absorbed.
Despite claims by manufacturers, the use of OTC products alone does not cause weight loss. Herbal weight-loss products or preparations called “fat burners” are even more misleading. These products may contain a combination of ma huang (a botanical source of ephedrine), white willow (a source of salicin), Hoodia gordonii, and/or guarana or kola nut (a source of caffeine). These agents are stimulants, which theoretically increase the metabolism and help the body break down fat. Nevertheless, there is no evidence that they are effective for weight loss. In addition, ma huang has been linked to serious side effects such as heart attacks, seizures, and death. Chromium also is a popular ingredient in weight-loss products, but there is no evidence that chromium has any effect on weight loss.
As with obesity in adults, many factors contribute to the rising rates of childhood obesity. Changing diet and decreasing physical activity are believed to be the two most important causes for the recent increase in the incidence of child obesity. Because childhood obesity often persists into adulthood and is associated with numerous chronic illnesses, children who are obese are often tested for hypertension, diabetes, hyperlipidemia, and fatty liver. Treatments used in children are primarily lifestyle interventions and behavioral techniques, although efforts to increase activity in children have had little success. In the United States, medications are not FDA approved for use in this age group. Multi-component behaviour change interventions that include changes to dietary and physical activity may reduce BMI in the short term in children aged 6 to 11 years, although the benefits are small and quality of evidence is low.
The overall goal for older adults who are obese is to help them make permanent lifestyle changes such as dietary modifications, increased exercise, and implementation of community supports. However, the older adult population presents with unique challenges that may prevent them from being able participate in certain physical activities preventing them from being able to lose weight.
Surgery. In general, weight-loss surgery (called bariatric surgery) may be considered if your BMI is 40 or greater, or your BMI is 30-35 or greater and you have at least one medical condition directly related to obesity. In addition, you must have participated in a structured weight loss program without success.
Obese parents can affect if their children become overweight or obese. A parent’s weight can change the DNA their children have. NHLBI is interested in how these DNA changes affect whether the child grows up to be overweight or obese.
The study also showed that obesity rates were consistently higher among women and African-Americans than for men and whites. For example, among people aged 20-29, 20% of whites and 35% of African-Americans were obese.
I’m running in the NYC Marathon in November to celebrate my 55th birthday and raise money for the Pancreatic Cancer Action Network, in memory of a friend who succumbed to the disease last year. Here’s an update on my training schedule for this week:
Aging baby boomers are smoking and drinking less, but overweight and obesity are on the rise, according to a new report from the U.S. Census Bureau. That’s especially concerning when you consider the many other diseases and disabilities—including arthritis, type 2 diabetes, heart disease, and hindered mobility—that can come with excess body weight.
A retrospective chart review of 96 residents in six intermediate care facilities in the United States found an association between anorexia and poor weight status and confusion in 42 residents.8 A prospective six-month study involving 309 residents of an intermediate nursing home in suburban midwestern United States found the primary reasons for weight changes to be acute illness, dementia and changes in the mucous membranes of the mouth and gums.9
Jump up ^ Zhang, Y; Proenca, R; Maffei, M; Barone, M; Leopold, L; Friedman, JM (Dec 1, 1994). “Positional cloning of the mouse obese gene and its human homologue”. Nature (Research Support). 372 (6505): 425–32. Bibcode:1994Natur.372..425Z. doi:10.1038/372425a0. PMID 7984236.
Oral nutritional supplements can be quite beneficial in preventing or reversing weight loss among elderly adults. Beverages such as Ensure are high in calories and nutrients, and are very convenient for seniors who have a limited ability to prepare nutritious meals. Seniors may need assistance from caregivers or family members to consistently supplement their nutrition so as to achieve maximum benefit.
In Chile, corporate interests delayed passage of the law for almost a decade, and on two occasions there were so many lobbyists crowding Congressional hearings for the bill that the Senate president was forced to suspend the sessions and clear the room.
Melania Lizano is a gynecologist with 20 years of experience practicing medicine, specializing in high-risk pregnancy and gynecologic diseases. She has a Masters degree in nutrition and is certified to teach Perfect Health: Ayurvedic Lifestyle and Primordial Sound Meditation . She uses her knowledge in holistic health and mind-body medicine in her medical practice, where she treats patients in a holistic, integrative way, and promotes healthy eating and lifestyle habits in women Learn more about Melania’s practice at melanializano…Read more
Hedlund J, Hansson L-O, örtqvist Å. Short-and long-term prognosis for middle-aged and elderly patients hospitalized with community-acquired pneumonia: impact of nutritional and inflammatory factors. Scand J Infect Dis 1995; 27: 32–37.
In a paper published in the online journal PLOS ONE, University of Adelaide researchers compared the health status of Baby Boomers (born from 1946-1965) and Generation X (1966-1980) at the same age range of 25-44 years.
For example, your BMI doesn’t show whether your weight is fat or muscle. If you’re a super-fit athlete, your muscle might put you in the “overweight” or “obese” range. Or, if you’re elderly and have lost muscle mass over the years, your BMI could be normal, but you’re not in as good shape as you think.
 Institute of Medicine and National Research Council. Weight Gain during Pregnancy: Reexamining the Guidelines. Washington, D.C.: The National Academies Press; 2009. http://www.ncbi.nlm.nih.gov/books/NBK32813.
Learn what key stakeholders engage with most by joining 3BL Media March 12 at 2 p.m. ET for a free, hour-long “Lunch & Learn” webcast. Included will be a review of top performing messaging from companies and nonprofits actively communicating about sustainability and CR, followed by an overview of 3BL Media’s services.
Weight-loss medication choices are more limited in older adults. This shortens the list of available medications for weight-loss. Side effects, existing medical conditions and interactions with other medications are the major barriers in prescribing weight-loss medications in the elderly. Bariatric surgery is being increasingly considered in older adults as well. The existing medical problems, surgical risk and benefits from the surgery need to be closely analyzed by the medical team and discussed with the patient to ensure an optimal decision and a satisfactory outcome.
A study done in Sweden compared the rates of diabetes and hypertension in two groups of obese patients: those who underwent surgery and those who didn’t. Each group had similar body weight at baseline (the start of the study). At two years, diabetes and high blood pressure were lower in the patients treated with surgery.
How did the most educated and wealthiest generation of Americans to date allow its collective health to fall by the wayside? The American lifestyle has largely shifted from active to sedentary and from community-oriented to socially isolating. Adults experience more stress in their hectic daily lives, which breeds depression and health problems, such as hypertension and high blood pressure. The net result of those factors is poor health and chronic ailments.
Baby boomers are currently in mid-life and over the next several decades they will swell the ranks of those aged 65 and over. Their entry into this age group will have a significant impact in a number of areas but particularly in relation to the type and extent of health services required. Obesity is a major health issue for this cohort as its members are significantly over-represented in both the overweight and obese categories compared to the rest of the population. In addition, they are significantly more likely to have multiple risk factors. This review considers how alterations to lifestyle, initiated by the rapid social changes of the last half century, might have contributed to obesity within this cohort. In providing this broad overview it focuses on how increased affluence and changes to everyday institutions have affected the cultures around food consumption. This includes a consideration of both the internal and external ways in which eating environments are now constructed. This review suggests that further research is needed to identify the factors which facilitate or constrain healthy ageing in the baby boom cohort. Research along these lines also needs to consider both macro- and micro-level changes to the social context within which these factors arise. This is essential as the high levels of obesity in this cohort may reflect both an individual and a structural lag in adapting lifestyles and policies to meet the needs of this very different social environment.
Scientists have made tremendous strides in understanding obesity and in improving the medication treatment of this important disease. In time, better, safer, and more effective obesity medications will be available. But currently there is still no “magic cure” for obesity. The best and safest way to lose fat and keep it off is through a commitment to a lifelong process of proper diet and regular exercise. Medications should be considered helpful adjuncts to diet and exercise for patients whose health risk from obesity clearly outweigh the potential side effects of the medications. Medications should be prescribed by doctors familiar with the patients’ conditions and with the use of the medications. Medication(s) and other “herbal” preparations with unproven effectiveness and safety should be avoided.